Genome Sciences applies its integrated proteomics

platform for the discovery and development of diagnostic and therapeutic produc

“What’s interesting about this finding is that the disease course in the individuals with low-activity COMT looked remarkably like idiopathic schizophrenia,” said Reiss, who hopes to use this and future data to develop a model for other causes of schizophrenia.

COMT they inherit; high-high, high-low and low-low all seem to provide enough COMT activity to get the job done (though some combinations confer a mild advantage for some cognitive tasks).

“Although this deletion probably causes less than 5 percent of schizophrenia cases, it’s the only well-defined genetic risk factor we have right now,” said Reiss.

The parties will then compare Monogram’s predictions of response based upon eTag assay analysis with actual clinical outcomes. Merck KGaA will make payments to Monogram for the project